Motor networks below the site of spinal cord injury (SCI), and their reconfiguration after loss of central inputs, are poorly understood but remain of great interest in SCI research. Harley et al. (J Neurophysiology 113: 3610-3622, 2015) report a striking locomotor recovery paradigm in the leech H. verbana with features that are functionally analogous to SCI. They propose that this well-established neurophysiological system could potentially be repurposed to provide a complementary model to investigate basic principles of homeostatic compensation relevant to SCI research.
- homeostatic plasticity
- motor network
- spinal cord injury
- Copyright © 2015, Journal of Neurophysiology