Table 3.

Pain-related activation in directed search sites

Regionxyzt-Scores 3-a
Alert control 3-b S134−18574.13
S242−16174.49
ACC12−2443.04
83322.72
IC3010−22.80
Hypnosis control 3-c S139−25573.35
S239−19203.06
ACC03453.11
IC321383.41
Increased-pain intensity 3-d S142−26595.04
S240−12143.10
ACC85483.11
IC3120−52.82
Decreased-pain intensity 3-e S136−25573.90
S247−16252.64
ACC1217302.81
IC311553.69
351803.61
  • Stereotaxic coordinates (x = medial-lateral,x > 0 denotes right hemisphere; y = anterior-posterior; z = superior-inferior) based on theTalairach and Tournoux (1988) atlas. S1 and S2, primary and secondary somatosensory cortices; ACC, anterior cingulate cortex; IC, insular cortex.

  • F3-aT α = 2.5 (see methods);

  • F3-b  alert control 47°C–alert control 35°C;

  • F3-c  hypnosis control 47°C–hypnosis control 35°C;

  • F3-d  increased-pain intensity–hypnosis control 35°C;

  • F3-e  decreased-pain intensity–hypnosis control 35°C.