Table 1.

Cell type abundances in the mouse MOB

ClassNumber (×103)Quantification MethodReference
GABAergic interneurons
sSAC87.2TH-labeled cells in GLParrish-Aungst et al. 2007
87.2Average
PGC324.1GAD65-GFP- and/or GAD67-labeled cells – TH-labeled cells in GLParrish-Aungst et al. 2007
324.1Average
EPL-IN55.7CRH-Cre-labeled cell density in EPL × EPL volumeHuang et al. 2013
53.4CRH-Cre-labeled cell density in EPL × EPL volumeGarcia et al. 2016
54.6 (53.4–55.7)Average (range)
dSAC9.2Σ(GABAARα1-, KV2.1-, KV3.1b-, KV4.3-labeled cells in rat IPL/GCL) × mouse-to-rat MC ratioEyre et al. 2009
11.5Σ(GABAARα1-, Chrna2-Cre-labeled cells in mouse IPL/GCL)Burton et al. 2017
10.4 (9.2–11.5)Average (range)
GC641.2Σ(GAD65-GFP- and/or GAD67-labeled cells in MCL/GCL)Parrish-Aungst et al. 2007
1,000.0NeuN-labeled cells in GCLRichard et al. 2010
820.6 (641.2–1,000.0)Average (range)
Glutamatergic neurons
MC38.4Large cells in MCLBenson et al. 1984
38.4Large cells in MCLRoyet et al. 1998
12.0~10% of neurons in MCLParrish-Aungst et al. 2007
33.0Large cells in MCLRichard et al. 2010
30.4 (12.0–38.4)Average (range)
TC17.5GAD65-GFP and GAD67-negative neurons in EPLParrish-Aungst et al. 2007
17.5Average
ETC388.7GAD65-GFP and GAD67-negative neurons in GLParrish-Aungst et al. 2007
189.1Σ(vGluT1-, vGluT2-, vGluT3-labeled cell density in GL – 40% vGluT3 [vGluT1/3, vGluT2/3 coexpression]) × GL volumeTatti et al. 2014
288.9 (189.1–388.7)Average (range)
Glomeruli
Glomeruli1.8Large cresyl violet-enclosed neuropil structures in GLRoyet et al. 1988
1.7Large cresyl violet-enclosed neuropil structures in GLPomeroy et al. 1990
3.8Large vGluT2-labeled structures in GLRichard et al. 2010
2.4 (1.7–3.8)Average (range)
  • Layer volumes averaged from Parrish-Aungst et al. (2007) and Richard et al. (2010). Mouse-to-rat MC ratio taken from Royet et al. (1998).